Gut microbes can influence the development of such diseases as obesity and diabetes. Bile acids occur naturally in human gut as they play a key in digestion and elimination of toxins. The pool of these bile acids can be affected by enzymes known as bile hydrolases that are produced by the gut microbes. By controlling the ability of these microbes to secrete the enzymes, the amounts of bile acids in the intestine can be regulated. This in turn leads to lower levels of fats and cholesterol in the blood and liver as they are targeted to generate energy. The net result is a decrease in weight. These microbes and their products can be utilized to treat obesity and other metabolic diseases.
Microbes and their components can help decrease weight.
Bon Voyage in the Microbial World.